https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Sex-dependent association between circulating irisin levels and insulin resistance in healthy adults https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23390 Wed 11 Apr 2018 14:11:03 AEST ]]> DHA-enriched fish oil reduces insulin resistance in overweight and obese adults https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39169 n = 38) or 2 g corn oil (CO) /day (control, n = 35) for 12 weeks in a double-blind randomised controlled trial. A fasting blood sample was collected at 0 and 12 weeks for assessment of IR, glucose and blood lipid profile. Sixty-eight participants completed the intervention. Compared with CO (n = 32), FO (n = 36) significantly reduced fasting insulin by -1.62 μIU/L (95%CI: -2.99, -0.26,) (p = 0.021) and HOMA-IR by -0.40 units (95%CI: -0.78, -0.02, p = 0.038). Higher insulin and HOMA-IR at baseline were associated with greater reductions in the FO group (p < 0.001). There was no interaction between sex and treatment for the change in insulin (p-interactionsex*treatment = 0.816) or HOMA-IR (p-interactionsex*treatment = 0.825). DHA-enriched FO reduces IR in adults with abdominal obesity, however, sex-dependent differences were not evident in this study.]]> Fri 20 May 2022 16:31:18 AEST ]]>